Rather than trying to find the best browser / add-ons, you may be better off using multiple browsers for clearly defined separate tasks. Cookies are confined to each browser.
If you have a Google account use Google Chrome for things signed into your Google account and nothing else. The only exception might be to visit websites to feed Google false or confusing information about yourself.
Use another browser for Google sites you use not signed into Google. Maybe you don't want your YouTube watch history tied to a Google identity. Never sign into Google on this browser.
If you use Facebook / Meta / IG etc. probably best use a separate browser for that.
You could have another browser (one of the hardened ones) for general browsing and perhaps another for shopping. A browser for shopping could have / may need more lenient settings than you use for general browsing.
My top picks would be: -
Librewolf (a hardened Firefox)
Mullvad (a hardened Firefox)
Firefox (but harden it)
Brave
A little behind those would be Ungoogled Chromium and way behind that would be just about everything else: Chromium, Chrome, Edge, Safari, Vivaldi, Opera.
https://privacytests.org/
There is Waterfox, it had been bought by System1 but apparently it's independent again. I have Basilisk on my Windows drive, but I don't use Windows for much web browsing now so I can't really say if it's good or bad, same for Pale Moon.
For add-ons I use uBlock Origin (for YouTube ads since I never figured out how to block those using my Pi-Hole) and sometimes Privacy Badger. There is an add-on for blocking JS (except stuff you allow) called NoScript, but I haven't used it.
Keep in mind that the more add-ons you use the more unique your browser becomes, and quite quickly too. This allows browser 'fingerprinting'.
An example setup might be: -
Google (signed in) - Chrome (no add-ons)
Google (never signed in) - Ungoogled Chromium + uBlock Origin
Facebook (OMG) - Firefox (hardened) or Mullvad
General browsing - Librewolf + NoScript
Shopping - Brave + uBlock Origin
OR
Google (never signed in) - Ungoogled Chromium + uBlock Origin
General browsing - Librewolf + NoScript
Shopping - Brave + uBlock Origin
OR
Google (never signed in) - Ungoogled Chromium + uBlock Origin
Everything else - Librewolf + NoScript
You know what you use the web for. Some entities will need greater separation than others simply because they have their code almost everywhere.
Whatever you use you'll probably want to set your browsers to clear cookies after every restart, or maybe even more frequently. I used to not do that since it was a hassle signing into everything again after a restart, but now I use Keepass XC for my passwords it's not that big of a deal.
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